Academisch Medisch Centrum - Universiteit Van Amsterdam (amc-uva)

This study tests a personalized plan to monitor and treat polyps in the stomach and duodenum of people with familial adenomatous polyposis (FAP), a condition that raises the risk of colorectal and upper GI cancers. Researchers will enroll 1,000 adults with FAP and follow them ove…

This study looks at whether people with well-controlled eczema can safely extend the time between their dupilumab injections from every 2 weeks to every 3 or 4 weeks. About 216 adults with controlled atopic dermatitis will be randomly assigned to one of three dosing schedules. Re…

Some people with long COVID have ongoing symptoms like severe fatigue, possibly because their immune system attacks their own body. This study tests a treatment called immunoadsorption, which filters the blood to remove harmful antibodies. About 70 adults with long COVID and thes…

This study looks at people with esophageal or stomach cancer that has spread to only a few places (oligometastases). All participants get 4 months of standard drug therapy, then are randomly assigned to either have local treatment (surgery or radiation) right away or after anothe…

This international study compares two minimally invasive surgical techniques for removing benign or pre-cancerous tumors from the left side of the pancreas. 256 patients will be randomly assigned to either laparoscopic (surgeon uses hand-held tools) or robot-assisted surgery. Res…

This study is testing a procedure called Duodenal Mucosal Resurfacing (DMR) for people with type 2 diabetes. Doctors use a scope to treat the lining of the first part of the small intestine. The goal is to see if this one-time procedure, and possibly a repeat treatment, can help …

This study tests a portable EEG device called StrokePointer that ambulance crews can use on people with suspected stroke. The goal is to quickly identify patients with a large vessel occlusion stroke who need to go directly to a hospital equipped for clot removal. About 275 adult…

This study tests whether using virtual reality (VR) to simulate the workplace can help cabin crew on sick leave for mental health reasons return to work faster. About 118 participants will either receive standard care or standard care plus at least one VR session where they virtu…

This study looks at how left ventricular diastolic dysfunction (a stiff heart muscle) affects recovery in women after heart surgery. Researchers will compare 1,000 male and female patients to find differences in complications and outcomes. The goal is to use this information to i…