Ultrasound-Guided ventilation aims to cut ARDS deaths
NCT ID NCT05492344
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using lung ultrasound to personalize ventilator settings can reduce deaths in people with acute respiratory distress syndrome (ARDS). About 538 adults on breathing machines will be assigned to either standard care or a personalized plan based on their lung ultrasound pattern. The main goal is to see if this approach lowers the chance of dying within 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
personalized mechanical ventilation guided by lung ultrasound
What this could lead to
If successful, this approach could become a standard way to set ventilators for ARDS patients, potentially lowering the death rate from this serious lung condition.
What could go wrong
This is a large trial, but the intervention is complex and depends on staff training. The benefit may be small or not apply to all ARDS types.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam UMC, location AMC
RECRUITINGAmsterdam, North Holland, 1105 AZ, Netherlands
Contact Email: •••••@•••••
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Amsterdam UMC, location VUmc
RECRUITINGAmsterdam, North Holland, 1081HV, Netherlands
Contact
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Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
RECRUITINGBari, Italy
Contact
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Bispebjerg Hospital
RECRUITINGCopenhagen, Denmark
Contact
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Centralny Szpital Kliniczny MSWiA
RECRUITINGWarsaw, Poland
Contact
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Chu-Brugmann
RECRUITINGBrussels, Belgium
Contact
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Evaggelismos Hospital
RECRUITINGAthens, Greece
Contact
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Galway University Hospitals
RECRUITINGGalway, Ireland
Contact
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Nordsjaellands Hospital
RECRUITINGHillerød, Denmark
Contact
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Ospedale Generale Regionale F. Miulli
RECRUITINGAcquaviva delle Fonti, Bari, Italy
Contact