Ultrasound-Guided ventilation aims to cut ARDS deaths

NCT ID NCT05492344

Recruiting now Disease control Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using lung ultrasound to personalize ventilator settings can reduce deaths in people with acute respiratory distress syndrome (ARDS). About 538 adults on breathing machines will be assigned to either standard care or a personalized plan based on their lung ultrasound pattern. The main goal is to see if this approach lowers the chance of dying within 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: personalized mechanical ventilation guided by lung ultrasound
What this could lead to: If successful, this approach could become a standard way to set ventilators for ARDS patients, potentially lowering the death rate from this serious lung condition.
What could go wrong: This is a large trial, but the intervention is complex and depends on staff training. The benefit may be small or not apply to all ARDS types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ARDS, HUMAN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARDS, HUMAN LUNG ULTRASOUND MECHANICAL VENTILATION

Contacts and locations

Locations

Amsterdam UMC, location AMC
RECRUITING

Amsterdam, North Holland, 1105 AZ, Netherlands
Amsterdam UMC, location VUmc
RECRUITING

Amsterdam, North Holland, 1081HV, Netherlands
Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
RECRUITING

Bari, Italy
Bispebjerg Hospital
RECRUITING

Copenhagen, Denmark
Centralny Szpital Kliniczny MSWiA
RECRUITING

Warsaw, Poland
Chu-Brugmann
RECRUITING

Brussels, Belgium
Evaggelismos Hospital
RECRUITING

Athens, Greece
Galway University Hospitals
RECRUITING

Galway, Ireland
Nordsjaellands Hospital
RECRUITING

Hillerød, Denmark
Ospedale Generale Regionale F. Miulli
RECRUITING

Acquaviva delle Fonti, Bari, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.