Balloon blasts fat in arteries: could it prevent heart attacks?

NCT ID NCT07107971

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a drug-coated balloon can reduce fatty deposits in heart arteries better than standard medications alone. Researchers will enroll 400 adults who recently had a heart-related event (acute coronary syndrome). Participants will get either the balloon treatment plus medication or medication only, and doctors will use imaging to track plaque changes over 9 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel-coated balloon

What this could lead to

If it works, this could offer a new way to stabilize dangerous heart plaques and reduce the risk of future heart attacks.

What could go wrong

This is an early-stage trial with 400 participants, so results may not apply to everyone. The balloon treatment also carries risks like vessel injury or allergic reaction to the drug.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome atherosclerosis cardiovascular disorder coronary artery disorder coronary atherosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Amsterdam UMC

    RECRUITING

    Amsterdam, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••