Sugar test during surgery may unlock secrets of fatty liver disease

NCT ID NCT07326865

First seen Jan 11, 2026 · Last updated Jun 20, 2026 · Updated 26 times

Summary

This study looks at how the liver reacts to a sugar injection during bariatric surgery in people with obesity, comparing those with and without fatty liver disease (MASLD). Forty adults will receive either a sugar solution or salt water during surgery, and small tissue samples will be taken to measure changes in gene activity. The goal is to understand why MASLD develops and how the liver handles sugar, which could lead to better ways to diagnose or treat the condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AMC

    RECRUITING

    Amsterdam, North Holland, 1105AZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

labeled glucose (intravenous)

What this could lead to

If successful, this study could reveal how the liver processes sugar differently in people with MASLD, pointing toward new ways to understand or treat the disease.

What could go wrong

This is a small, early-stage observational study (40 participants) that does not test a treatment. Results may not apply to broader populations or lead directly to therapies.

Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.