MASLD
Clinical trials for MASLD explained in plain language.
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Could a stomach tuck reverse fatty liver?
Disease control Recruiting nowThis study tests whether a minimally invasive procedure called endoscopic sleeve gastroplasty (ESG), which reduces stomach size by 70%, can help reverse fatty liver disease (MASH) in people with obesity. Researchers will compare ESG plus lifestyle changes to lifestyle changes alo…
Matched conditions: MASLD
Phase: NA • Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Peanuts vs. fatty liver: a 12-Week diet test begins
Disease control Recruiting nowThis study tests whether eating 50 grams of peanuts daily for 12 weeks can improve liver markers and gut health in adults with metabolic fatty liver disease (MASLD). 125 participants will be randomly assigned to either eat peanuts or stick to their regular diet. Researchers will …
Matched conditions: MASLD
Phase: NA • Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Old heart drug could be new hope against fatty liver
Disease control Recruiting nowThis study tests whether a low dose of digoxin, a drug normally used for heart problems, can help people with a severe type of fatty liver disease called NASH (also known as MASH). The trial will involve 144 adults with biopsy-confirmed NASH and liver scarring. Participants will …
Matched conditions: MASLD
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New portable scanner could replace needle biopsies for fatty liver disease
Diagnosis Recruiting nowThis study is testing a new, portable device called LiverScope that uses magnetic fields to check the liver for disease, similar to an MRI but smaller and easier to use. Researchers want to see if LiverScope gives the same results as a standard MRI. About 26 adults with a type of…
Matched conditions: MASLD
Sponsor: University of California, San Diego • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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New ultrasound test could spot fatty liver in kids without needles or scary scans
Diagnosis Recruiting nowThis study is testing whether advanced ultrasound techniques can accurately detect fatty liver disease (MASLD) in children aged 9 to 18. Researchers will compare ultrasound results to MRI scans and blood tests in 120 children with risk factors for the condition. If the ultrasound…
Matched conditions: MASLD
Sponsor: University of California, San Diego • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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New Scope-Based ultrasound could spare patients liver biopsies
Diagnosis Recruiting nowThis study is testing a new way to measure liver scarring using an endoscopic ultrasound with special software. About 300 adults with suspected liver disease will undergo this new scan, a standard liver biopsy, and another non-invasive test. The goal is to see if the new techniqu…
Matched conditions: MASLD
Sponsor: Olympus Corporation of the Americas • Aim: Diagnosis
Last updated Jun 26, 2026 16:57 UTC
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Sugar test during surgery may unlock secrets of fatty liver disease
Knowledge-focused Recruiting nowThis study looks at how the liver reacts to a sugar injection during bariatric surgery in people with obesity, comparing those with and without fatty liver disease (MASLD). Forty adults will receive either a sugar solution or salt water during surgery, and small tissue samples wi…
Matched conditions: MASLD
Phase: NA • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Sugar shock: could fructose be wrecking your gut and raising diabetes risk?
Knowledge-focused Recruiting nowThis study looks at how eating a lot of fructose (a type of sugar) changes the bacteria in your gut and affects your risk for type 2 diabetes and fatty liver. Thirty adults with obesity, diabetes, or fatty liver will eat a high-fructose or high-glucose diet for 12 days, then swit…
Matched conditions: MASLD
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Scientists hunt for hidden genes that drive fatty liver to cirrhosis
Knowledge-focused Recruiting nowThis study aims to find genetic differences that make some people with fatty liver disease develop severe liver damage or cancer. Researchers will analyze DNA from 2880 adults, including those with advanced disease and healthy controls. The goal is to create better risk tests and…
Matched conditions: MASLD
Phase: NA • Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New VA program aims to catch silent liver disease in veterans
Knowledge-focused Recruiting nowThis study tests a new care pathway for non-alcoholic fatty liver disease (NAFLD) in VA primary care. The pathway automatically identifies at-risk patients and educates providers. Researchers will compare this approach to usual care in 32 primary care teams to see if it increases…
Matched conditions: MASLD
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC