Could a daily dose of citrus fiber tame fatty liver inflammation?
NCT ID NCT07093346
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests whether a daily supplement of pectin — a fiber found in citrus peels — can reduce inflammation and improve gut bacteria in adults with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), a common form of fatty liver. For six weeks, participants take either pectin mixed with cocoa powder or a placebo (cocoa powder alone). Researchers measure changes in blood markers of inflammation, gut microbiome composition, and metabolic health indicators like BMI and blood sugar.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a dietary supplement called pectin, a fiber from citrus peels, taken daily for 6 weeks
- What this could lead to
- If pectin reduces inflammation and improves gut bacteria, it could point toward a simple dietary approach to help manage fatty liver disease.
- What could go wrong
- This is a small, early-stage trial with only 45 participants. Pectin is a common food ingredient, so major risks are low, but its effects on liver inflammation are unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nottingham Clinical Research Facility at Nottingham University Hospitals NHS Trust
RECRUITINGNottingham, NG7 2UH, United Kingdom
-
Sir Peter Mansfield Imaging Centre, University of Nottingham
RECRUITINGNottingham, NG7 2QX, United Kingdom
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University of Nottingham
RECRUITINGNottingham, United Kingdom, NG7 2UH, United Kingdom
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