University Of Nottingham

This study is looking back at the medical records of children with a rare bone disease called XLH. The goal is to see if a lower starting dose of the standard treatment drug, burosumab, works just as well as the current higher standard dose to control blood phosphate levels. Rese…

This study is testing whether specific 8-week exercise programs—one based on running, another on swimming or cycling—can reduce pain and improve function in adults with long-term lower back pain better than continuing their usual activities. Researchers will compare these two pro…

This study is testing if a safe, non-invasive brain stimulation technique can reduce the loudness and distress of tinnitus. Researchers will give 40 adults with tinnitus gentle electrical stimulation to the scalp to see if it changes brain activity linked to the condition. The go…

This University of Nottingham study explores whether a special ultrasound technique can improve memory in healthy adults. Researchers will apply focused ultrasound to specific brain areas while participants complete memory tests, measuring both immediate effects and longer-term c…

This study aims to understand how long-term pain conditions like chronic knee pain and fibromyalgia might change the way the brain sends signals to muscles. Researchers will compare adults over 40 with these conditions to pain-free volunteers. Participants will undergo pain sensi…

This study is testing a new, non-invasive ultrasound device called ZenBud that gently stimulates a nerve in the ear linked to relaxation. Researchers want to see if using the device causes measurable changes in things like heart rate, brain waves, mood, or thinking in healthy vol…

This study is testing if repeatedly squeezing the arm with a blood pressure cuff can improve how the brain regulates its blood flow in healthy older adults. Researchers will compare different schedules of these arm squeezes over six weeks. The goal is to gather information to hel…

This study aims to understand the experiences of people from ethnic minority backgrounds when accessing healthcare services at home or in community centers. Researchers will interview community members and healthcare providers to identify barriers and find ways to make these serv…

This study aims to understand how physical activity and inactivity affect the body and brain as people age. Researchers will ask 40 middle-aged adults to either increase their exercise to recommended levels or decrease their activity to match the average sedentary person for six …

This study aims to understand why some cancer patients develop liver injury after taking immunotherapy drugs called checkpoint inhibitors. Researchers will observe 160 patients who either develop this liver injury or are starting the drugs, collecting blood samples to look for bi…

This study is a survey to understand the experiences and choices of adults with type 1 diabetes regarding automated insulin delivery systems, often called 'artificial pancreas' or hybrid closed-loop systems. Researchers want to learn what factors influence people's decisions when…