MRI scans reveal gut Drug's secrets in healthy volunteers

NCT ID NCT07569419

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how linaclotide, a drug for constipation, affects fluid in the gut. Researchers will use MRI scans to see where the drug works in the small and large intestines. The goal is to learn more about its effects, which could help design future studies for conditions like cystic fibrosis. Healthy volunteers aged 18-60 will take the drug or a placebo and have MRI scans.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sir Peter Mansfield Imaging Centre

    RECRUITING

    Nottingham, NG7 2QX, United Kingdom

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