University Of Nottingham
Clinical trials sponsored by University Of Nottingham, explained in plain language.
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Beetroot and vitamin c: a natural way to lower blood pressure?
Disease control CompletedThis study looked at whether taking beetroot juice (which is rich in nitrates) together with vitamin C could lower blood pressure and improve blood vessel health in overweight adults aged 50-75. Fifteen participants took either the combination, beetroot juice alone, or a placebo.…
Phase: NA • Sponsor: University of Nottingham • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Simple breathing exercises may ease long COVID breathlessness
Symptom relief CompletedThis study tested a breathing exercise program for people with long COVID who still feel short of breath. 40 adults took part to see if the exercises could improve their breathing and daily activities compared to usual care. The goal was to find a simple way to help manage this c…
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Talking therapy shows promise for trauma in people with learning disabilities
Symptom relief CompletedThis study tested whether an adapted form of Narrative Exposure Therapy (NET) is acceptable and helpful for adults with mild learning disabilities who have experienced trauma. Thirteen participants completed the therapy, which involved talking through their life events in a struc…
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Chewing gum may be the surprising new tool to recover smell and taste
Symptom relief CompletedThis pilot study tested whether chewing flavored gum twice a day for 12 weeks could help people recover their sense of smell and taste. Thirty adults with smell or taste loss were split into three groups: one chewed flavored gum, one smelled liquid flavors, and one waited. The st…
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Sound waves in the ear: a new hope for tinnitus?
Symptom relief CompletedThis study tested whether people with tinnitus can tell if they are receiving real or fake ultrasound stimulation of the vagus nerve in the ear. Twenty adults with constant tinnitus for at least six months took part. The goal was to see how well the blinding worked and what side …
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New toolkit aims to ease chronic pain at work – but is it feasible?
Symptom relief CompletedThis study tested whether a toolkit called Pain at Work (PAW) can help employees with chronic pain manage their symptoms and stay productive. Around 380 workers from different workplaces in England took part, with some using the toolkit plus support calls and others receiving usu…
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Knee pain relief without pills? fiber and exercise show promise
Symptom relief CompletedThis study tested whether a fiber supplement (inulin) and/or app-based exercises could reduce knee pain in 117 adults with osteoarthritis. Participants were split into groups: placebo, diet only, exercise only, or both. The main goal was to see if pain scores improved over time. …
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 26, 2026 18:45 UTC
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Mindfulness boosts dietitian resilience in small trial
Symptom relief CompletedThis study tested whether a 4-week online mindfulness course could improve resilience and reduce stress and burnout in UK dietitians. Thirty registered dietitians took part, with some attending the course and others on a waitlist. Researchers measured their well-being before, rig…
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Jun 26, 2026 13:28 UTC
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Brain scans reveal how gut talks to brain in obesity
Knowledge-focused CompletedThis study used MRI to examine how the brain and gut communicate after eating different types of drinks in people with obesity and healthy weight. Researchers gave participants a high-fat drink or a carbohydrate drink and scanned their brains and stomachs. The goal was to develop…
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Ultrasound zaps brain to sharpen memory in healthy volunteers
Knowledge-focused CompletedThis study tested whether a non-invasive technique called theta-burst focused ultrasound can improve visual working memory in healthy adults. 24 participants received targeted ultrasound to specific brain areas while their brain activity was monitored with EEG. The goal was to se…
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Hospital staff reveal secrets to preventing falls in confused patients
Knowledge-focused CompletedThis study looked at how healthcare workers prevent accidental falls in hospital patients who have temporary or permanent loss of cognitive function (like confusion or dementia). Researchers used simulations and group discussions with nurses, therapists, and doctors to understand…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Small study reveals hidden hurdles to exercise for severe depression
Knowledge-focused CompletedThis study interviewed 12 people with persistent major depression who were referred to a group exercise program. Researchers wanted to understand what makes it easier or harder for them to take part. The goal is to help clinics create exercise programs that better fit the needs o…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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What drives choice of artificial pancreas? survey reveals patient priorities
Knowledge-focused CompletedThis completed study surveyed 166 adults with type 1 diabetes to understand what factors influence their choice of hybrid closed-loop (artificial pancreas) systems. Participants included those already using, waiting to start, or considering such technology. The goal was to learn …
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Could a simple drug tweak metabolism in obesity?
Knowledge-focused CompletedThis study tested whether sodium phenylbutyrate can lower levels of branched chain amino acids (BCAAs) in the blood of obese and prediabetic men. High BCAAs are linked to insulin resistance and type 2 diabetes. Researchers also looked at how the drug affects blood sugar, insulin …
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Home workouts may boost cancer Patients' cell power
Knowledge-focused CompletedThis study looked at how prostate and colorectal cancer affect mitochondria—the energy factories in cells—and whether a 4-week home exercise program could improve them. Fifteen men awaiting surgery did either resistance or high-intensity interval training at home. Researchers mea…
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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What makes muscles weak in frail seniors after a hip break?
Knowledge-focused CompletedThis study looked at 80 frail older adults who had hip surgery after a fall. Researchers took small muscle samples to measure fat, protein, and gene activity. The goal was to understand whether muscle amount or muscle function matters more for recovery. This is a knowledge-gather…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Why are black African/Caribbean people at higher diabetes risk? stomach emptying may hold clues.
Knowledge-focused CompletedThis study compared how quickly the stomach empties a sugary drink in 30 white Europeans and 30 people of Black African or Caribbean descent. The goal was to understand why Black African/Caribbean people have a higher risk of type 2 diabetes. Researchers measured blood sugar, ins…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Tiny study asks: does MBT work for Over-60s?
Knowledge-focused CompletedThis small study looked at whether Mentalization-Based Therapy (MBT) helps people aged 60 and older who struggle in relationships. Researchers recruited 3 participants and used interviews and questionnaires to see if the therapy improved their ability to understand their own and …
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Care home staff get a boost in fall prevention confidence
Knowledge-focused CompletedThis study looked at a program designed to help care home staff feel more confident in preventing falls. Researchers interviewed 24 staff members and observed group meetings to see what topics were covered and if confidence improved. The goal was to understand what makes such a p…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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MRI scans reveal gut secrets in obesity battle
Knowledge-focused CompletedThis study used MRI scans to compare how quickly food leaves the stomach and how the gut responds to eating in 12 people with obesity and 12 healthy-weight individuals. Researchers also measured gut hormones and blood flow to learn more about why some people remain obese. The goa…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Orange juice may boost insulin sensitivity in overweight women
Knowledge-focused CompletedThis study looks at whether drinking orange juice every day can help overweight women become more sensitive to insulin, a hormone that controls blood sugar. Thirty-six women will drink either orange juice or a sugary orange drink for three months. Researchers will measure insulin…
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New model aims to stop falls in care homes
Knowledge-focused CompletedThis study worked with care home staff, residents, and health experts to create a new plan for preventing falls in older adults living in care homes. Researchers held workshops and surveys with 31 participants to design the model and decide how to measure its success. The goal is…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Skipping breakfast might boost muscle building, small study suggests
Knowledge-focused CompletedThis study looked at whether fasting for about 16 hours overnight (instead of the usual 10) changes how the body handles food and builds muscle. Nine healthy young men took part. Researchers measured blood sugar, insulin, and muscle protein building after a protein drink. The goa…
Phase: NA • Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Simple tests may gauge fitness in seniors
Knowledge-focused CompletedThis study looked at 64 adults over 65 to see if easy bedside tests—like measuring muscle size with ultrasound—can predict cardiorespiratory fitness. Participants did a cycling test to measure their maximum oxygen uptake. The goal is to find simpler ways to assess fitness without…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:42 UTC