Cure My Disease

Don't miss your cure!

 Log in / Sign up

Orange juice may boost insulin sensitivity in overweight women

NCT ID NCT01201603

Knowledge-focused Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether drinking orange juice every day can help overweight women become more sensitive to insulin, a hormone that controls blood sugar. Thirty-six women will drink either orange juice or a sugary orange drink for three months. Researchers will measure insulin sensitivity, blood fats, and gene activity in fat tissue to see if the antioxidants in orange juice make a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
orange juice
What this could lead to
If it works, this could point toward dietary recommendations for improving insulin sensitivity in overweight individuals.
What could go wrong
This is a small, early-stage study with only 36 participants. Results may not apply to the general population, and any benefits could be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Start date

Jul 2010

Finished

Nov 2013

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * pre-menopausal or post-menopausal and taking HRT * BMI 27-35kg/m2 * HOMA-IR value \> 1.5 * healthy Exclusion Criteria: * pregnant or breast feeding, * any metabolic or endocrine abnormalities, * clinically significant abnormalities on screening, * fasting glucose \> 6.0mmol/l, * taking medication other than the contraceptive pill or HRT * herbal supplement use, * food allergies/intolerances related to the investigational product (citrus juices, fructose) * daily consumption of \>100ml citrus juices

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Insulin resistance are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Insulin resistance Obesity

Contacts and locations

Locations

  • University of Nottingham

    Nottingham, Notts, NG7 2UH, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.