What makes muscles weak in frail seniors after a hip break?

NCT ID NCT04764617

Completed Knowledge-focused Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 80 frail older adults who had hip surgery after a fall. Researchers took small muscle samples to measure fat, protein, and gene activity. The goal was to understand whether muscle amount or muscle function matters more for recovery. This is a knowledge-gathering study, not a treatment test.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help identify why some frail older patients recover poorly after hip surgery, pointing toward ways to improve muscle health and recovery.
What could go wrong: This is an observational study, not a treatment trial. It aims to gather knowledge, not test a therapy, so it won't directly change patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Frailty hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FRAILTY SYNDROME

Contacts and locations

Locations

Queens Medical Centre; Department of Orthopaedics

Nottingham, NG72UH, United Kingdom

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