Sound waves in the ear: a new hope for tinnitus?

NCT ID NCT07291648

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether people with tinnitus can tell if they are receiving real or fake ultrasound stimulation of the vagus nerve in the ear. Twenty adults with constant tinnitus for at least six months took part. The goal was to see how well the blinding worked and what side effects occurred, not to measure tinnitus relief. The device, called ZenBud, uses focused ultrasound to stimulate the nerve, which may help normalize brain activity linked to tinnitus.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ultrasound Vagus Nerve Stimulation (U-VNS) using the ZenBud device

What this could lead to

If this approach works, it could point toward a non-invasive, targeted treatment for tinnitus that avoids the side effects of electrical stimulation.

What could go wrong

This is a very small, early-stage study (20 people) focused on blinding and side effects, not on whether the treatment actually reduces tinnitus. The device may not prove effective in larger trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tinnitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Nottingham

    Nottingham, United Kingdom