Ringing relief? migraine drugs tested for tinnitus in new study
NCT ID NCT07655440
First seen Jun 24, 2026
Summary
Many people with migraine also suffer from tinnitus, a persistent ringing in the ears. This trial will compare two types of migraine preventives—newer anti-CGRP drugs and older medications like antidepressants and blood pressure drugs—to see which better reduces tinnitus symptoms. 120 adults with both conditions will be randomly assigned to one of the two groups and followed for 24 weeks. The study is run by Stanford University and is not yet recruiting.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
migraine preventive medications (anti-CGRP drugs like galcanezumab, erenumab, eptinezumab, atogepant; and conventional drugs like amitriptyline, nortriptyline, propranolol, verapamil)
What this could lead to
If it works, this could point toward a new treatment option for tinnitus in people with migraine, potentially reducing the ringing in their ears.
What could go wrong
This is a Phase 4 trial with only 120 participants, so results may not apply to everyone. It is also possible that neither drug class helps tinnitus more than the other.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.