Ringing relief? migraine drugs tested for tinnitus in new study
NCT ID NCT07655440
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
Many people with migraine also suffer from tinnitus, a persistent ringing in the ears. This trial will compare two types of migraine preventives—newer anti-CGRP drugs and older medications like antidepressants and blood pressure drugs—to see which better reduces tinnitus symptoms. 120 adults with both conditions will be randomly assigned to one of the two groups and followed for 24 weeks. The study is run by Stanford University and is not yet recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- migraine preventive medications (anti-CGRP drugs like galcanezumab, erenumab, eptinezumab, atogepant; and conventional drugs like amitriptyline, nortriptyline, propranolol, verapamil)
- What this could lead to
- If it works, this could point toward a new treatment option for tinnitus in people with migraine, potentially reducing the ringing in their ears.
- What could go wrong
- This is a Phase 4 trial with only 120 participants, so results may not apply to everyone. It is also possible that neither drug class helps tinnitus more than the other.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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