Brain scans reveal how gut talks to brain in obesity
NCT ID NCT05437653
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study used MRI to examine how the brain and gut communicate after eating different types of drinks in people with obesity and healthy weight. Researchers gave participants a high-fat drink or a carbohydrate drink and scanned their brains and stomachs. The goal was to develop better imaging methods and understand why some people may be heavier than others.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Nutritional drinks (high-fat emulsion and carbohydrate drink)
- What this could lead to
- If successful, this could help explain how the brain and gut interact to control appetite, potentially pointing toward new approaches for managing obesity.
- What could go wrong
- This is a small, early-stage imaging study with only 24 participants. It is designed to develop methods, not test a treatment, so direct benefits are uncertain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Nottingham
Nottingham, NG7 2RD, United Kingdom
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