Brain scans reveal how gut talks to brain in obesity
NCT ID NCT05437653
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study used MRI to examine how the brain and gut communicate after eating different types of drinks in people with obesity and healthy weight. Researchers gave participants a high-fat drink or a carbohydrate drink and scanned their brains and stomachs. The goal was to develop better imaging methods and understand why some people may be heavier than others.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nutritional drinks (high-fat emulsion and carbohydrate drink)
What this could lead to
If successful, this could help explain how the brain and gut interact to control appetite, potentially pointing toward new approaches for managing obesity.
What could go wrong
This is a small, early-stage imaging study with only 24 participants. It is designed to develop methods, not test a treatment, so direct benefits are uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Nottingham
Nottingham, NG7 2RD, United Kingdom