MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Clinical trials for MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE) explained in plain language.
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Time-Restricted eating: a new weapon against fatty liver?
Disease control Recruiting nowThis study tests whether limiting food intake to an 8-hour window each day (without counting calories) can reduce liver fat in people with obesity and a type of fatty liver disease called MASLD. Seventy-two participants will either follow this eating pattern plus standard advice,…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: Nantes University Hospital • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Lifestyle overhaul tested as fatty liver fix
Disease control Recruiting nowThe UNMASK study is testing whether a 16-week program of Mediterranean diet and regular exercise can reduce liver fat and scarring in people with metabolic fatty liver disease (MASLD). Researchers will enroll 450 adults and track changes in liver health using scans and blood test…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Can Mountain-Like workouts help fatty liver? small trial aims to find out
Disease control Recruiting nowThis study tests whether aerobic exercise in simulated altitude (normobaric hypoxia) can improve body composition and metabolism in people with MASLD, a type of fatty liver disease. Twenty sedentary adults with MASLD will walk on a treadmill for 8 weeks, either in mild altitude o…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: University of Trieste • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can olive oil melt away fatty liver? new study investigates
Disease control Recruiting nowThis study is testing whether adding extra virgin olive oil to the diet can improve liver fat, inflammation, and blood sugar in people with MASLD (fatty liver disease) who are overweight. Researchers will give 60 participants either 3 or 9 tablespoons of olive oil daily for a per…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can a liver drug help people with HIV? new trial aims to find out
Disease control Recruiting nowThis study tests whether resmetirom, a drug already approved for another liver condition, can safely reduce liver fat in people with HIV who also have fatty liver disease (MASLD). About 120 adults with well-controlled HIV will take either resmetirom or a placebo daily for 24 week…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: PHASE2 • Sponsor: Naga P. Chalasani • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Gut bacteria boost may fight fatty liver
Disease control Recruiting nowThis study tests whether a daily probiotic capsule can reduce liver fat and stiffness in adults with moderate fatty liver disease (MASLD). Sixty participants will take either the probiotic or a placebo for 6 months, with liver scans and blood tests at the start, 3 months, and 6 m…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: PHASE2 • Sponsor: AB Biotics, SA • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New program aims to reduce heart disease risk in mexican-origin adults with fatty liver
Disease control Recruiting nowThis study tests whether a community health worker-led program can help Mexican-origin adults with fatty liver disease (MASLD) better understand their heart disease risk and make healthier lifestyle changes. About 45 participants and their family members or friends will take part…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: University of Arizona • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Could a ketone drink help teens with fatty liver disease?
Disease control Recruiting nowThis study tests whether a daily ketone ester drink can reduce liver fat and improve how the body handles sugar in adolescents and young adults with obesity and a fatty liver condition called MASLD. Forty participants will be randomly assigned to receive either the ketone drink o…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Free veggies for kids with fatty liver: a new hope?
Disease control Recruiting nowThis study tests whether giving $80 per month in fruit and vegetable vouchers to families with food insecurity can improve liver health in children with MASLD (fatty liver disease). The study will enroll 48 children aged 6-17 who are already receiving care at UCSF clinics. Resear…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 26, 2026 12:44 UTC
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New portable scanner could replace needle biopsies for fatty liver disease
Diagnosis Recruiting nowThis study is testing a new, portable device called LiverScope that uses magnetic fields to check the liver for disease, similar to an MRI but smaller and easier to use. Researchers want to see if LiverScope gives the same results as a standard MRI. About 26 adults with a type of…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Sponsor: University of California, San Diego • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Spleen stiffness scan could spare liver patients painful biopsies
Diagnosis Recruiting nowThis study is testing whether measuring spleen stiffness with a special ultrasound probe can detect advanced liver scarring in people with metabolic fatty liver disease (MASLD). Researchers will follow 500 adults for up to several years to see if the test predicts serious liver p…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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New ultrasound test could spot fatty liver in kids without needles or scary scans
Diagnosis Recruiting nowThis study is testing whether advanced ultrasound techniques can accurately detect fatty liver disease (MASLD) in children aged 9 to 18. Researchers will compare ultrasound results to MRI scans and blood tests in 120 children with risk factors for the condition. If the ultrasound…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Sponsor: University of California, San Diego • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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New ultrasound test could make liver fat detection quick and painless
Diagnosis Recruiting nowThis study is testing a new ultrasound method to measure fat in the liver without needles or expensive scans. It involves 110 adults with or at risk for MASLD, a common liver condition linked to obesity and diabetes. If successful, this tool could make liver health checks easier …
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: ContextVision AB • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Gut bugs linked to liver damage in new study
Knowledge-focused Recruiting nowThis study looks at how gut bacteria produce certain chemicals that might worsen fatty liver disease (MASLD). Researchers will collect stool, blood, and urine samples from 24 people with the condition and healthy volunteers. They aim to identify which bacteria are responsible for…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Swedish Mega-Study scans 1,400 for clues to heart, lung, and liver disease
Knowledge-focused Recruiting nowThis study is re-examining 1,400 adults in Stockholm to find early signs and risk factors for heart, lung, and liver diseases. Participants will get advanced scans, blood tests, and questionnaires. The goal is to better understand how these diseases develop and how to predict the…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Sponsor: Danderyd Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Food insecurity linked to worse liver disease in kids – new study investigates
Knowledge-focused Recruiting nowThis study looks at how not having reliable access to healthy food affects liver disease severity in children with MASLD (a fatty liver condition). Researchers will track diet quality and liver health in 160 children aged 6–17. The goal is to understand if poor diet due to food i…
Matched conditions: MASLD (METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE)
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:46 UTC