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Can olive oil melt away fatty liver? new study investigates

NCT ID NCT07412444

Recruiting now Disease control Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether adding extra virgin olive oil to the diet can improve liver fat, inflammation, and blood sugar in people with MASLD (fatty liver disease) who are overweight. Researchers will give 60 participants either 3 or 9 tablespoons of olive oil daily for a period, then measure changes in liver fat using a special ultrasound-like scan and blood tests. The goal is to find the best amount of olive oil to help manage this common liver condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
extra virgin olive oil
What this could lead to
If it works, this could show that adding more olive oil to a Mediterranean diet helps reduce liver fat and improve metabolic health in people with MASLD.
What could go wrong
This is a small, early-stage study with only 60 participants, so results may not apply to everyone. The higher dose (9 tablespoons) adds many calories, which could offset benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MASLD - METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE OVERWEIGHT

Contacts and locations

Locations

  • UOS Data Science

    RECRUITING

    Castellana Grotte, Italy, 70013, Italy

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