Spleen stiffness scan could spare liver patients painful biopsies
NCT ID NCT07440511
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether measuring spleen stiffness with a special ultrasound probe can detect advanced liver scarring in people with metabolic fatty liver disease (MASLD). Researchers will follow 500 adults for up to several years to see if the test predicts serious liver problems like cirrhosis or liver cancer. The goal is to replace invasive liver biopsies with a quick, painless scan.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
spleen stiffness measurement (non-invasive ultrasound-based test)
What this could lead to
If successful, this could provide a simple, needle-free way to detect advanced liver scarring early and predict complications in people with fatty liver disease.
What could go wrong
This is an observational study, not a treatment trial. The test may not prove accurate enough to replace current methods, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione Policlinico Universitario A. Gemelli IRCCS
RECRUITINGRome, 00168, Italy
Contact Email: •••••@•••••