Could a new drug tame fatty liver disease? early trial aims to find out

NCT ID NCT05945537

Recruiting now Disease control Sponsor: Inipharm Australia Pty Ltd Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This early-stage trial is testing an experimental drug called INI-822 to see if it is safe and tolerable. It involves healthy volunteers and people with MASH, a type of fatty liver disease. The study will give different doses of the drug or a placebo to see how the body handles it and whether it causes any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: INI-822
What this could lead to: If successful, this could lead to a new treatment option for MASH, a common liver disease with no approved therapies.
What could go wrong: This is an early-stage trial focused on safety, not effectiveness. The drug may not work or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatohepatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS

Contacts and locations

Locations

Box Hill Hospital, Level 1, 5 Arnold street
RECRUITING

Box Hill, Victoria, 3128, Australia
Campbelltown Hospital, Level 10, building A, Campbelltown Hospital, Therry Road,
NOT_YET_RECRUITING

Campbelltown, New South Wales (nsw), 2560, Australia
Flinders Medical Centre, Flinders Medical Centre, Flinders
RECRUITING

Bedford Park, South Australia (SA), 5042, Australia
Genesis Research Services, Ground Floor, 239/245 Denison Street Broadmeadow
RECRUITING

Newcastle, New South Wales (nsw), 2292, Australia
Princess Alexandra Hospital
RECRUITING

Woolloongabba, Queensland, 4102, Australia
Ramsay Health North Shore, North Shore Private, 03 Westbourne Street
NOT_YET_RECRUITING

Saint Leonards, New South Wales (nsw), 2065, Australia
Royal Prince Alfred Hospital
RECRUITING

Camperdown, New South Wales, 2050, Australia
St. Vincent's Hospital Melbourne
RECRUITING

Fitzroy, Victoria, 3065, Australia
TrialsWest Pty Ltd, 90 Anstruther Road
RECRUITING

Mandurah, Western Australia (WA), 6210, Australia
University of the Sunshine Coast Clinical Trials (Birtinya), UniSC Clinical Trials Vitality Village, Level 4, Tenancy 410, 5 Discovery Court
RECRUITING

Birtinya, Queensland (qld), 4575, Australia
Westmead Hospital, Storr Liver Centre, Level 2, A/B Block, Westmead Hospital Corner Hawkesbury and Darcy Roads
RECRUITING

Westmead, Westmead, 2145, Australia

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