Could a fatty liver fuel Alzheimer's? new scan aims to find out
NCT ID NCT06453915
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new way to use PET scans to measure inflammation in both the liver and brain at the same time. Researchers will scan 12 adults with fatty liver disease using two different tracers (18F-FDG and 18F-DPA-714) to see if the new method can reliably detect brain inflammation linked to liver disease. The goal is to develop a practical imaging tool to study how liver inflammation might contribute to Alzheimer's disease and related dementias.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
18F-FDG and 18F-DPA-714 (imaging tracers)
What this could lead to
If successful, this imaging method could help researchers study how liver inflammation affects brain health, potentially pointing toward new ways to prevent or treat Alzheimer's disease.
What could go wrong
This is a very small, early-phase study focused on developing a measurement tool, not a treatment. The method may not prove reliable or useful in larger, more diverse populations.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UC Davis EXPLORER Molecular Imaging Center
RECRUITINGSacramento, California, 95816, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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