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New scan could replace risky vein test for Hormone-Driven high blood pressure

NCT ID NCT05188872

Recruiting now Diagnosis Sponsor: First Affiliated Hospital of Fujian Medical University Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study tests whether a special PET/CT scan using a tracer called 68Ga-Pentixafor can accurately diagnose primary aldosteronism, a common cause of high blood pressure. The scan aims to identify which adrenal gland is overproducing the hormone aldosterone, potentially replacing the current gold-standard test that involves threading a catheter into the adrenal veins. Researchers will also use the scan before and after a minimally invasive treatment called superselective adrenal artery embolization to see how well it tracks treatment effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
68Ga-Pentixafor, a radioactive tracer used in PET/CT imaging
What this could lead to
If successful, this imaging method could offer a less invasive and more accurate way to diagnose primary aldosteronism and guide treatment decisions.
What could go wrong
This is an early-stage diagnostic study with 100 participants, so results may not apply to everyone. The tracer's accuracy compared to the current gold standard is still unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSITRON EMISSION TOMOGRAPHY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University

    RECRUITING

    Fuzhou, Fujian, 350005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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