Time-Restricted eating: a new weapon against fatty liver?

NCT ID NCT07378072

Recruiting now Disease control Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This study tests whether limiting food intake to an 8-hour window each day (without counting calories) can reduce liver fat in people with obesity and a type of fatty liver disease called MASLD. Seventy-two participants will either follow this eating pattern plus standard advice, or receive standard advice alone, for 12 weeks. The main goal is to see if liver fat decreases more with time-restricted eating.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: time-restricted eating (eating only within an 8-hour window each day)
What this could lead to: If it works, this could offer a simple, calorie-free way to reduce liver fat in people with obesity and fatty liver disease.
What could go wrong: This is a small, early-stage trial with only 72 people. The results may not apply to everyone, and sticking to an 8-hour eating window can be hard to maintain long-term.

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MASLD - METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE

Contacts and locations

Locations

CHU Angers
NOT_YET_RECRUITING

Angers, 49993, France
CHU Bordeaux
NOT_YET_RECRUITING

Bordeaux, 33404, France
CHU Dijon-Bourgogne
NOT_YET_RECRUITING

Dijon, 21000, France
CHU Lyon
NOT_YET_RECRUITING

Lyon, 69495, France
CHU Marseille
NOT_YET_RECRUITING

Marseille, 13000, France
CHU Montpellier
NOT_YET_RECRUITING

Montpellier, 34000, France
CHU Nantes
RECRUITING

Nantes, 44093, France
CHU Rennes
NOT_YET_RECRUITING

Rennes, 35000, France
Hôpital Européen Georges Pompidou
NOT_YET_RECRUITING

Paris, 75015, France

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