Cure My Disease

Don't miss your cure!

 Log in / Sign up

Lifestyle overhaul tested as fatty liver fix

NCT ID NCT07652151

Recruiting now Disease control Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The UNMASK study is testing whether a 16-week program of Mediterranean diet and regular exercise can reduce liver fat and scarring in people with metabolic fatty liver disease (MASLD). Researchers will enroll 450 adults and track changes in liver health using scans and blood tests. The goal is to see if lifestyle changes alone can improve this common condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mediterranean diet plus structured exercise (150 min/week moderate or 75 min/week high-intensity)
What this could lead to
If successful, this could show that a simple lifestyle program can reduce liver fat and scarring in people with fatty liver disease, pointing toward a non-drug treatment option.
What could go wrong
This is an early-stage observational study with no control group, so results may not prove cause and effect. The lifestyle changes are intensive and may be hard for many to maintain long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MASLD - METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Fibrosis metabolic dysfunction-associated steatotic liver disease Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MASLD - METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE

Contacts and locations

Locations

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Internal Medicine and Liver Transplantation Unit

    NOT_YET_RECRUITING

    Roma, Italy

  • Hacettepe University

    NOT_YET_RECRUITING

    Ankara, Turkey (Türkiye)

  • Hospital Universitario Virgen del Rocío de Sevilla

    RECRUITING

    Seville, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.