Shorter radiation course for esophageal cancer shows promise in new trial

NCT ID NCT07632079

Recruiting now Disease control Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a shorter, more intense radiation schedule combined with chemotherapy for people with locally advanced esophageal cancer. The goal is to see if this approach is safe and feasible, and to reduce side effects like low white blood cell counts. About 60 adults will receive 20 radiation sessions over 4 weeks instead of the usual 28 sessions over 5.5 weeks.

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Conditions

The condition(s) this trial relates to.

carcinoma of esophagus esophageal cancer gastroesophageal cancer gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED ESOPHAGEAL OR GE JUNCTION CANCER

Contacts and locations

Locations

Amsterdam UMC
RECRUITING

Amsterdam, Netherlands
Gelre Ziekenhuizen
NOT_YET_RECRUITING

Apeldoorn, Netherlands
Maastro
NOT_YET_RECRUITING

Maastricht, Netherlands
Radboud UMC
NOT_YET_RECRUITING

Nijmegen, Netherlands
Radiotherapiegroep
NOT_YET_RECRUITING

Apeldoorn, Netherlands
UMCG
RECRUITING

Groningen, Netherlands
Zuyderland Medisch Centrum
NOT_YET_RECRUITING

Heerlen, Netherlands

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