Which wrinkle treatment lasts longest? Head-to-Head trial of all five botox products
NCT ID NCT06448676
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This trial compares the effectiveness and safety of all five commercially available botulinum toxin type A products for treating frown lines in women aged 18 and older. Participants receive injections into facial muscles and take weekly smartphone photos to track changes. The goal is to determine which product works best and how long the effects last.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
botulinum toxin type A
What this could lead to
If this trial succeeds, it could help doctors choose which botulinum toxin product works best and lasts longest for frown lines.
What could go wrong
This is a phase 4 trial comparing existing products, so no new treatment is being discovered. Results may not apply to men or other uses of botulinum toxin.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Nuceiva Safety Study for Glabellar Lines (NCT05481931)
- Wrinkle Treatment Study QM1114-DP (NCT05148000)
- Micro-Coring Device for Wrinkles – NCT03228641
- Botox Injection Depth for Frown Lines Trial NCT05766683
- Obagi Saypha MagIQ for Facial Aging - NCT07421544
- CU-20101 vs Botox for Frown Lines (NCT06585696)
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Faceland
RECRUITINGAmsterdam, Netherlands
Contact Phone: •••-•••-••••
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Faceland
RECRUITINGEindhoven, Netherlands
Contact Phone: •••-•••-••••
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Faceland
RECRUITINGUtrecht, Netherlands
Contact Phone: •••-•••-••••