Neck wrinkle fix: filler study compares two injection methods
NCT ID NCT04162496
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study tests Restylane Refyne, a hyaluronic acid filler, for treating horizontal neck lines in adults with mild to moderate wrinkles. Each participant receives the filler on one side of the neck with a cannula and on the other side with a needle, allowing a direct comparison. The goal is to see which method works better and causes fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Restylane Refyne (hyaluronic acid filler) injected via cannula or needle
- What this could lead to
- If successful, this could show that Restylane Refyne safely reduces neck wrinkles, offering a cosmetic option for aging skin.
- What could go wrong
- This is a small, early study with only 26 participants, so results may not apply widely. Risks include bruising, swelling, or allergic reactions.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Siperstein Dermatology
Boynton Beach, Florida, 33472, United States
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