Can a dissolving thread smooth away wrinkles?

NCT ID NCT06404372

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial tests a new type of dissolvable thread, called the Demetech Barbed PDO Suture, to see if it can safely reduce wrinkles in the midface (cheek area). About 57 adults with mild to moderate wrinkles will receive the thread, which is designed to lift and smooth the skin over time. Researchers will check how much wrinkles improve at 3 and 6 months, and track any side effects over a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Demetech Barbed PDO Suture, an absorbable thread used to lift and smooth midface wrinkles
What this could lead to
If successful, this could offer a non-surgical, temporary option for reducing midface wrinkles with minimal downtime.
What could go wrong
This is a small, early-stage study (57 people) and results may not apply to everyone. Risks include possible side effects like pain, swelling, or thread migration, and the effect is temporary.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cosmetic Injectables Center

    Sherman Oaks, California, 91423, United States

  • Dr. Kristin Tarbet Facial Plastic Surgery

    Bellevue, Washington, 98004, United States

  • Rejuva Medical Aesthetics

    Los Angeles, California, 90025, United States

  • Vedas Med Spa

    The Woodlands, Texas, 77381, United States

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