New device aims to smooth wrinkles by removing tiny skin cores

NCT ID NCT03228641

Completed Symptom relief Sponsor: Cytrellis Biosystems, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested a micro-coring device on 45 people to see if it can safely reduce wrinkles and skin laxity in the face. The device uses tiny hollow needles to remove small cores of skin, which triggers the body to produce new collagen and elastin. The goal was to improve wrinkle and laxity scores by at least one grade.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: micro-coring device
What this could lead to: If it works, this could offer a non-surgical option to reduce facial wrinkles and sagging skin.
What could go wrong: This is a small pilot study with only 45 people, so results may not apply to everyone. The device is still experimental and may not work as well as expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Facies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FACIAL AND NECK SKIN LAXITY WRINKLE

Contacts and locations

Locations

Dr A Jay Burns Cosmetic Surgery

Dallas, Texas, 75231, United States
Laser & Skin Center of Northern CA

Sacramento, California, 95816, United States
Laser & Skin Surgery Center of NY

New York, New York, 10016, United States
Miami Dermatology and Laser Institute

Miami, Florida, 33173, United States
Nashville Center for Laser & Facial Surgery

Nashville, Tennessee, 37203, United States
SkinCare Physicians

Chestnut Hill, Massachusetts, 02467, United States

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