Smarter brain stimulation could give Parkinson's patients more good hours each day

NCT ID NCT06909045

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways of delivering deep brain stimulation (DBS) to people with Parkinson's disease: adaptive DBS, which adjusts stimulation in real time based on brain signals, and continuous DBS, which delivers constant stimulation. About 130 adults who already have a DBS device will be randomly assigned to one of the two methods. The goal is to see if adaptive DBS increases the amount of time during the day when movement is good and without bothersome side effects, over a six-month period.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Amsterdam UMC

    RECRUITING

    Amsterdam, Netherlands

  • HagaZiekenhuis

    NOT_YET_RECRUITING

    The Hague, Netherlands

  • Maastricht UMC+

    NOT_YET_RECRUITING

    Maastricht, Netherlands

  • UZ Leuven

    NOT_YET_RECRUITING

    Leuven, Belgium

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