Frozen hope: new study aims to help boys become fathers after cancer

NCT ID NCT02872532

Recruiting now Disease control Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study offers boys aged 0-17 the chance to freeze testicular tissue before undergoing treatments like chemotherapy or radiation that could cause permanent infertility. The tissue is stored for potential future use to achieve pregnancy. Researchers will track whether transplanted tissue leads to successful pregnancies and live births.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: testicular tissue cryopreservation (procedure)
What this could lead to: If successful, this could allow boys who lose fertility due to cancer treatment to father biological children later in life.
What could go wrong: This is an early-stage collection study; it's unknown if the frozen tissue will successfully restore fertility. The procedure itself carries surgical risks.

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Conditions

The condition(s) this trial relates to.

cancer cancer-related condition infertility disorder Klinefelter syndrome neoplasm spermatic cord torsion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER CANCER-RELATED CONDITION INFERTILITY

Contacts and locations

Locations

Mayo Clinic in Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

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