Mouthwash may stop chemo mouth sores in their tracks

NCT ID NCT07287826

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a dexamethasone mouthwash can prevent moderate to severe mouth sores caused by chemotherapy in adults with cancer. Participants use the mouthwash four times daily during chemo for up to 8 weeks. Researchers compare their outcomes to a historical group to see if the rinse reduces pain and soreness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexamethasone mouthwash

What this could lead to

If it works, this could offer a simple, low-cost way to prevent painful mouth sores during chemotherapy, improving comfort and quality of life.

What could go wrong

This is a small, early-phase study with only 45 participants and no placebo group, so results may not be conclusive. The mouthwash may not reduce sores for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer stomatitis chemotherapy-induced oral mucositis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Woman's Hospital

    RECRUITING

    Baton Rouge, Louisiana, 70817, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact