Mouthwash may stop chemo mouth sores in their tracks
NCT ID NCT07287826
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a dexamethasone mouthwash can prevent moderate to severe mouth sores caused by chemotherapy in adults with cancer. Participants use the mouthwash four times daily during chemo for up to 8 weeks. Researchers compare their outcomes to a historical group to see if the rinse reduces pain and soreness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexamethasone mouthwash
- What this could lead to
- If it works, this could offer a simple, low-cost way to prevent painful mouth sores during chemotherapy, improving comfort and quality of life.
- What could go wrong
- This is a small, early-phase study with only 45 participants and no placebo group, so results may not be conclusive. The mouthwash may not reduce sores for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Woman's Hospital
RECRUITINGBaton Rouge, Louisiana, 70817, United States
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