Cancer survivors may finally ditch heart pills: major trial underway

NCT ID NCT06183437

Recruiting now Disease control Sponsor: Dinesh Thavendiranathan Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study looks at whether cancer survivors who had heart problems from their cancer treatment can safely stop taking heart failure medications once their heart function is back to normal. About 335 adults who have finished cancer therapy and are on heart medications will be randomly assigned to either continue or stop their heart drugs. The goal is to see if stopping the medications is as safe as continuing them, by checking for any return of heart problems within one year.

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Conditions

The condition(s) this trial relates to.

cancer Cardiotoxicity chemotherapy-induced toxicity heart failure neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTINEOPLASTICS TOXICITY CANCER CARDIAC TOXICITY CARDIOTOXICITY HEART FAILURE

Contacts and locations

Locations

Baker Heart and Diabetes Institute
RECRUITING

Melbourne, Victoria, 3004, Australia
Barts Health NHS Trust, University College London
RECRUITING

London, London, United Kingdom
Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Cardio-Oncology Clinic, MAHI, University of Alberta Hospital
RECRUITING

Edmonton, Alberta, T6G 1C9, Canada
Guy's and St Thomas' NHS Foundation Trust (Royal Brompton Hospital)
NOT_YET_RECRUITING

London, United Kingdom
Hamilton General Hospital
NOT_YET_RECRUITING

Hamilton, Ontario, L8L 2X2, Canada
La Paz University Hospital
NOT_YET_RECRUITING

Madrid, 28046, Spain
Liverpool Heart and Chest Hospital
RECRUITING

Liverpool, L14 3PE, United Kingdom
Maria Sklodowska-Curie National Research Institute of Oncology
NOT_YET_RECRUITING

Warsaw, Poland
St Michael's Hospital
NOT_YET_RECRUITING

Toronto, Ontario, M5B 1W8, Canada
St. Boniface Hospital
RECRUITING

Winnipeg, Manitoba, R2H 2A6, Canada
University Health Network
RECRUITING

Toronto, Ontario, M5G2C4, Canada
University of California, Los Angeles
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States
University of Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, K1Y 4W7, Canada

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