CARDIOTOXICITY

This study tests a 6-month program of supervised exercise, heart risk management, and online support for young cancer survivors (ages 18-45) who have mild heart dysfunction. The goal is to see if this approach improves fitness and heart health better than standard advice. 336 par…

This study tests whether aggressively lowering blood pressure during breast cancer treatment is safer and more effective than standard care at preventing heart damage. About 130 women with breast cancer and high blood pressure will be assigned to either intensive or standard bloo…

This study tests whether using a high-efficiency air filter in the bedroom overnight can lower inflammation in adult cancer survivors living in polluted areas. Ten participants will have their air filtered for 14-day periods, alternating with sham filters, while their blood marke…

This study looks at whether cancer survivors who had heart damage from their cancer treatment, but whose heart function has since recovered, can safely stop taking heart failure medications. About 335 adults who finished cancer therapy at least 6 months ago and are currently on h…

This study tests whether empagliflozin, a drug used for diabetes, can prevent heart damage in cancer patients receiving strong chemotherapy (anthracyclines). About 220 adults with cancer but no prior heart failure will take either empagliflozin or a placebo daily for 12 months. T…

This study looks at whether a 12-week exercise program can improve heart and muscle function in women over 60 who had chemotherapy for breast cancer. Chemo can sometimes weaken the heart, and exercise might help. Researchers will compare a structured exercise program to a stretch…

This study aims to see if advanced imaging techniques, like special ultrasound and MRI, can find heart damage earlier in children, teens, and young adults who have had cancer treatment. Researchers will follow 400 participants to track heart problems that may appear during or aft…

This study aims to create a computer-based tool that can predict which cancer patients are at high risk of heart damage from certain treatments. Researchers will follow 600 patients in France for one year, collecting health data to train a machine learning model. The goal is to h…

This study tests whether special MRI scans can find early signs of heart damage in cancer patients receiving anthracycline chemotherapy. Current tests often miss this damage until it's advanced. About 93 participants will have MRI scans before, during, and after treatment to see …

This study watches people with HER2+ breast cancer that has spread, who are getting trastuzumab-based treatment. The main goal is to see how often heart problems happen, especially in those also taking beta blockers or other heart medications. A smaller part of the study tests if…