CARDIOTOXICITY

This study tests two different drugs—dexrazoxane and liposomal doxorubicin—to see which is safer and more effective at preventing heart failure in people with a type of lymphoma called DLBCL. All 60 participants will receive standard chemotherapy (R-CHOP or pola-R-CHP), and the g…

This study will test whether AI-enhanced 3D and 2D echocardiography (heart ultrasound) can detect chemotherapy-related heart damage as accurately as cardiac MRI. Researchers will compare these new imaging methods with standard ultrasound and MRI in 120 adults who have received po…

This study tests whether a drug called sotagliflozin can prevent heart, muscle, and fat damage caused by a common type of chemotherapy (anthracycline) in people with newly diagnosed lymphoma. About 60 adults who are scheduled to receive high-dose anthracycline will take either th…

This study tests whether a 16-week supervised exercise program can help breast cancer survivors improve their body's ability to switch between burning carbs and fats for energy. Researchers will enroll 44 women aged 18-70 who completed chemotherapy within the last 6 months and ar…

This study follows 100 women with early-stage breast cancer who are receiving standard chemotherapy or anti-HER2 therapy. Researchers will use heart ultrasounds and blood tests to look for early signs of heart damage. The goal is to find better ways to detect cardiac side effects…

This study tests a computer tool that helps doctors and cancer survivors decide together on the best heart-protective medications and tests. Researchers will enroll 60 cancer survivors at risk for heart problems. The goal is to see if the tool is easy to use and helps people foll…

This study will follow 400 people receiving a stem cell transplant to see how often they develop heart problems like heart attacks, irregular heartbeat, or heart failure. Researchers will use heart scans, blood tests, and other tools to find early warning signs. The goal is to be…