CARDIOTOXICITY
Clinical trials for CARDIOTOXICITY explained in plain language.
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Prescribing exercise to heal Chemotherapy-Damaged hearts
Disease control CompletedThis study tested whether a supervised aerobic exercise program could improve heart health in childhood cancer survivors. The participants, who had received a specific type of chemotherapy that can damage the heart, followed a 12-week exercise plan. Researchers measured changes i…
Matched conditions: CARDIOTOXICITY
Sponsor: Connecticut Children's Medical Center • Aim: Disease control
Last updated Apr 01, 2026 22:56 UTC
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Diabetes pill may shield hearts from chemo damage
Disease control CompletedThis study tested whether a diabetes drug called dapagliflozin could protect the heart in cancer patients receiving a common but potentially heart-damaging chemotherapy. 90 patients were randomly assigned to take either dapagliflozin or a placebo pill daily for four months alongs…
Matched conditions: CARDIOTOXICITY
Phase: PHASE2 • Sponsor: Hawler Medical University • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Shielding the heart from Chemo's hidden danger
Disease control CompletedThis study tested if giving a heart medication called carvedilol to breast cancer patients at higher risk of heart damage could protect their hearts during chemotherapy. It involved 68 women receiving specific cancer drugs (doxorubicin and/or trastuzumab). The goal was to see if …
Matched conditions: CARDIOTOXICITY
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Can exercise save young cancer survivors from heart disease?
Disease control CompletedThis pilot study tested whether a special exercise and lifestyle program is practical and safe for young cancer survivors who are at risk for heart problems. It involved 30 survivors aged 18-45 who had finished cancer treatment but had early signs of mild heart dysfunction. The m…
Matched conditions: CARDIOTOXICITY
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Mar 02, 2026 15:29 UTC
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Scientists track Radiation's hidden toll on cancer Patients' hearts
Knowledge-focused CompletedThis study aims to understand how two different types of radiation therapy affect the heart in breast cancer patients. Researchers followed 172 patients who were already enrolled in a larger radiation comparison trial. They measured heart function and collected blood samples befo…
Matched conditions: CARDIOTOXICITY
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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New scans aim to spot silent heart damage in cancer survivors
Knowledge-focused CompletedThis study aimed to find better ways to detect early heart damage caused by breast cancer treatments like chemotherapy and radiation. Researchers followed 150 patients for up to 10 years, using special heart scans and blood tests to look for early warning signs. The goal was to l…
Matched conditions: CARDIOTOXICITY
Sponsor: Oncology Institute of Southern Switzerland • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Scientists track heart risks in pioneering cancer treatment
Knowledge-focused CompletedThis study aimed to understand how CAR-T cell therapy, a powerful cancer treatment, affects the heart. Researchers followed 44 adults with leukemia or lymphoma, checking their heart function with scans and blood tests before and after treatment. The goal was to learn how often he…
Matched conditions: CARDIOTOXICITY
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC
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Doctors track heart risks in lung cancer treatment
Knowledge-focused CompletedThis study aimed to understand how often a specific type of heart problem occurs in people with advanced lung cancer who are taking targeted drugs called EGFR-TKIs. Researchers followed 100 patients to monitor their heart function before and during treatment. The goal was to gath…
Matched conditions: CARDIOTOXICITY
Sponsor: Taichung Veterans General Hospital • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC