Can a diabetes drug shield hearts from chemo damage?

NCT ID NCT06888505

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether dapagliflozin (Farxiga), a drug used for diabetes and heart failure, can prevent heart damage caused by anthracycline chemotherapy. 94 adults with cancer took either dapagliflozin or a placebo daily for four months alongside their chemo. Researchers measured heart function and blood markers to see if the drug offered protection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dapagliflozin (Farxiga)

What this could lead to

If it works, this could point toward a way to protect the heart during chemotherapy, reducing the risk of long-term heart damage.

What could go wrong

This is a small, early-phase trial with only 94 participants. The results may not apply to everyone, and the drug may not provide meaningful protection in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer cardiomyopathy due to anthracyclines Cardiotoxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Azadi Oncology Centre

    Duhok, Duhok Governorate, 42001, Iraq