Which radiation is safer for the heart? new study compares proton and photon therapy in breast cancer patients.

NCT ID NCT04361240

Completed Knowledge-focused Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 172 breast cancer patients to see how proton radiation compares to standard photon radiation in terms of heart health. Researchers measured heart function and blood markers before, during, and up to one year after treatment. The goal was to understand which type of radiation might be safer for the heart.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Cardiotoxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER CARDIOTOXICITY

Contacts and locations

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Locations

Abramson Cancer Center at University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Johns Hopkins

Baltimore, Maryland, 21287, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Northwestern Medicine

Warrenville, Illinois, 60555, United States
University of Alabama

Birmingham, Alabama, 35233, United States
University of Washington

Seattle, Washington, 98195, United States