Heart shield for chemo: new study tests carvedilol in breast cancer patients

NCT ID NCT04023110

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 29 times

Summary

This early-phase study tested whether giving the heart medication carvedilol to breast cancer patients at high risk for heart problems could safely protect their hearts during chemotherapy with doxorubicin and/or trastuzumab. 68 women with stage I-III breast cancer participated. The goal was to see if this risk-guided approach was safe, tolerable, and practical, not to prove it prevents heart failure. Results focus on heart function and medication adherence.

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Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

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