CARDIOTOXICITY
Clinical trials for CARDIOTOXICITY explained in plain language.
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Exercise may protect hearts of childhood cancer survivors
Disease control OngoingThis study looks at whether different levels of exercise can help the hearts of young adults who survived childhood cancer and were treated with a type of chemotherapy called anthracyclines. Twenty survivors between ages 18 and 39 will take part. The goal is to see if exercise ca…
Matched conditions: CARDIOTOXICITY
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Prostate cancer Treatment's hidden heart risk under the microscope
Knowledge-focused OngoingThis study follows 200 men with prostate cancer who are receiving hormone therapy (androgen deprivation therapy) for at least 6 months. Researchers want to understand how this treatment affects the heart, including changes in heart function and the risk of heart failure. They wil…
Matched conditions: CARDIOTOXICITY
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 17, 2026 03:23 UTC
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Smart patch could replace needle for heart check
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests if a wearable sensor can accurately estimate the heart's pumping ability (LVEF) in 50 adults who are already scheduled for an echocardiogram. The goal is to see if the sensor matches the standard ultrasound test. If successful, this could lead to easier, more fre…
Matched conditions: CARDIOTOXICITY
Sponsor: Skribe Medical • Aim: Knowledge-focused
Last updated May 17, 2026 03:15 UTC
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Can a simple exercise test predict heart risks in breast cancer patients?
Knowledge-focused OngoingThis study looks at how well a cardiopulmonary exercise test (CPET) can measure oxygen use in women with HER2-positive breast cancer who have mild heart problems from their cancer treatment. The goal is to see if this test can help predict how their heart and lungs will handle co…
Matched conditions: CARDIOTOXICITY
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:13 UTC
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Cancer Drugs' hidden heart impact under the microscope
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how immune checkpoint inhibitors, a type of cancer drug, affect the tiny blood vessels in the heart. Researchers will use heart scans and blood tests to check for changes in 25 people with breast or lung cancer. The goal is to learn more about potential heart …
Matched conditions: CARDIOTOXICITY
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 17, 2026 03:11 UTC
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Lung cancer Treatment's hidden heart risk under the microscope
Knowledge-focused OngoingThis study follows 221 people with stage II or III lung cancer to see how chemoradiation therapy affects the heart over two years. Participants undergo heart scans, blood tests, and surveys before, during, and after treatment. The goal is to better understand and detect heart dam…
Matched conditions: CARDIOTOXICITY
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 17, 2026 03:09 UTC
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Smartwatches keep watch on heart side effects of leukemia drugs
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 50 people with chronic lymphocytic leukemia who are starting treatment with acalabrutinib or zanabrutinib. Participants use wearable devices at home to monitor their heart rhythm and blood pressure. The goal is to learn how often these drugs cause high blood pr…
Matched conditions: CARDIOTOXICITY
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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15-Year study to uncover hidden heart risks in breast cancer therapy
Knowledge-focused OngoingThis study follows 200 women with breast cancer who are receiving chemotherapy drugs doxorubicin or trastuzumab. Researchers want to understand how these treatments affect the heart over time and how factors like race, income, and access to healthcare play a role. Participants wi…
Matched conditions: CARDIOTOXICITY
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC