Fasting before chemo: could a Plant-Based diet boost cancer treatment?

NCT ID NCT05359848

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study is testing whether intermittent fasting (calorie restriction on alternate days) combined with a plant-based protein diet can help cancer patients respond better to chemotherapy. The study will enroll 30 adults with various cancers who are scheduled for chemotherapy. The main goal is to see if this diet plan is practical and tolerable for patients, while also gathering early data on whether it might improve tumor shrinkage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
intermittent caloric restriction plus plant-based protein diet
What this could lead to
If this approach works, it could point toward a way to make chemotherapy more effective by using diet to enhance the body's response to treatment.
What could go wrong
This is a very small, early pilot study with only 30 participants, so results may not apply to everyone. The diet may be hard to follow, and it's not yet known if it actually improves outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University at Buffalo / Great Lakes Cancer Care

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University at Buffalo / Great Lakes Cancer Care

    RECRUITING

    Buffalo, New York, 14206, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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