Cheap, safe pill may spare kids chemo sickness

NCT ID NCT03118986

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 28 times

Summary

This study tests whether adding olanzapine, a safe and inexpensive drug already used in children for other conditions, can better control vomiting caused by strong chemotherapy. About 200 children receiving cancer treatment or stem cell transplants will be randomly assigned to get olanzapine or a placebo alongside standard anti-nausea medicines. The goal is to see if more children can avoid vomiting and the need for extra rescue drugs.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • All India Institute of Medical Sciences

    RECRUITING

    New Delhi, National Capital Territory of Delhi, 110029, India

    Contact Email: •••••@•••••

  • Cancer Care Manitoba

    RECRUITING

    Winnipeg, Manitoba, R3E 0V9, Canada

    Contact Email: •••••@•••••

  • Centre Hospitalier Universitaire Sainte-Justine,

    TERMINATED

    Montreal, Quebec, H3T 1C5, Canada

  • Columbia University/Morgan Stanley Children's Hospital

    WITHDRAWN

    New York, New York, 10032, United States

  • Hospital for Sick Children

    RECRUITING

    Toronto, Ontario, M5G 1X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-••••

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

    Contact Email: •••••@•••••

  • The Children's Mercy Hospital

    RECRUITING

    Kansas City, Missouri, 64108, United States

    Contact Phone: •••-•••-••••

  • University of California

    RECRUITING

    San Francisco, California, 94158, United States

    Contact Email: •••••@•••••

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599-7220, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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