ONCOLOGY

This early-stage trial is testing a new oral medication called NST-628 for adults with advanced solid tumors that have specific genetic changes in a key cancer growth pathway. The study aims to find a safe and effective dose and see if the drug can shrink tumors in patients who h…

This study is tracking 3000 cancer patients who take their anticancer pills at home instead of receiving injections in the hospital. Researchers want to see if a special support program helps patients take the right dose safely and avoid problems. The goal is to improve how docto…

This study aims to gather detailed information to make repeat radiation therapy safer for lung cancer survivors whose cancer has returned or who develop a new tumor in the chest. Researchers will follow 500 patients in Denmark to track severe side effects, survival, and quality o…

This is the first study in people testing a new oral medication called TRE-515 for advanced solid tumors that have stopped responding to standard treatments. The main goal is to find the highest safe daily dose and understand how the drug moves through the body. Researchers will …

This study is testing whether switching cancer patients who smoke to e-cigarettes is a helpful alternative when they refuse all standard quit-smoking treatments. Researchers will compare e-cigarette use to standard care in 208 patients to see which approach helps more people stop…

This study is testing if a special solution called taurolidine can prevent infections in the catheters used by children and young adults with cancer. Researchers will compare it to a standard saline solution to see which one better stops germs from growing inside the catheter. Th…

This study is testing a mobile phone app designed to help children who have finished cancer treatment manage their ongoing symptoms like fatigue, pain, and anxiety. For 12 weeks, 150 child survivors and their main caregiver will use the app, which includes personalized support fr…

This study is testing a community-based program designed to help cancer survivors and their support people living in persistent poverty areas improve their health. The program focuses on adapting healthy eating and physical activity approaches to fit the specific challenges these…

This study is testing if adding a drug called olanzapine to standard anti-nausea medicines can better control vomiting in children receiving very strong chemotherapy for cancer or before a stem cell transplant. It will involve about 200 children and teenagers. The main goal is to…

This study is testing whether personalized beauty and skincare services can help people with head and neck cancer feel better about their appearance during treatment. It will involve 55 adult patients who are starting cancer treatment. The main goal is to see if this supportive c…

This study is testing whether using a special walking platform every day helps older adults (age 65+) recover their normal walking speed after cancer surgery. Researchers will compare patients who use the platform to those who receive standard care. The main goal is to see if mor…

This study tests whether having children, teens, and their families set personal functional goals during a stem cell transplant hospital stay helps them stay more active and maintain their physical abilities. Researchers will compare a group using this goal-setting approach to a …

This study is testing a non-drug treatment called photobiomodulation (a type of light therapy) to see if it can help improve memory and thinking problems, often called 'chemobrain,' in women who have finished chemotherapy for breast cancer. Researchers will compare the results in…

This study is testing how well children and adults with conditions like cerebral palsy or cancer tolerate a new liquid food formula given through a feeding tube in their stomach. Over 28 days, researchers will check for digestive issues like vomiting or diarrhea and see if partic…

This study is testing whether offering financial counseling as a standard part of cancer care helps patients. Researchers will look at data from 40 patients and staff to see if this counseling reduces money stress, improves quality of life, and lessens emotional distress for peop…

This study is testing a decision-making support tool designed to help older adults with acute myeloid leukemia (AML) and their caregivers. It aims to reduce emotional distress and improve the quality of shared decisions about cancer treatment. The trial will compare the new tool …

This study aims to collect video and voice recordings from people with cancer to create a database for future research. Researchers want to use this data to train artificial intelligence (AI) to recognize signs of pain from facial expressions and speech patterns. The goal is to d…

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …

This study aims to understand how patients with advanced cancer feel about the idea of reducing or stopping some of their medications, a process called 'deprescribing.' Researchers will interview and survey about 325 patients to learn their attitudes and beliefs. The goal is to g…

This study aims to understand why some cancer patients develop autoimmune side effects when taking immunotherapy drugs called checkpoint inhibitors. Researchers will collect blood samples from 600 cancer patients before and during their immunotherapy treatment to study their immu…

This study aims to understand why some cancer patients develop serious side effects from immunotherapy drugs called checkpoint inhibitors. Researchers will follow 200 patients with solid tumors, collecting blood and stool samples before and during treatment to look for biological…

This study measures how eye pressure changes in women undergoing robotic surgery for gynecologic cancers. Researchers want to see if using different anesthesia methods affects eye pressure when patients are positioned head-down during surgery. The study involves 40 female patient…

This early-stage study is testing a new imaging agent, given as an injection, to see if it can safely and effectively show what's happening inside solid tumors. Researchers want to see if special PET scans using this tracer can detect changes in tumors after patients receive immu…

This study aims to collect and analyze information from 15,000 cancer patients in Italy's Campania region. It will look at how patients move through the healthcare system, what treatments they receive, and their outcomes. The goal is to understand current care patterns and find w…

This study aims to understand the long-term outcomes for women who froze eggs or ovarian tissue before cancer treatment. Researchers will track over 100 female cancer survivors to see if and how they use their preserved fertility options, and what factors influence their family-b…

This study is testing an education program called CTNow, designed to help cancer patients and their doctors in rural Hawaii learn more about clinical trials. The goal is to make it easier for patients to find out about and get referred to cancer research studies. The program uses…