New pill takes aim at Cancer's DNA repair

NCT ID NCT05055609

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 26 times

Summary

This early-stage trial tests an experimental pill called TRE-515 in people with advanced solid tumors that have not responded to standard treatments. The drug works by blocking a key enzyme cancer cells need to make DNA, potentially slowing tumor growth. The main goals are to find a safe dose and check for side effects, with about 94 participants expected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Carolina BioOncology Institute

    RECRUITING

    Huntersville, North Carolina, 28078, United States

    Contact

    Contact Phone: •••-•••-••••

  • UCLA

    RECRUITING

    Santa Monica, California, 90404, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

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