Can a Zinc-Based compound fight cancer?

NCT ID NCT06506643

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests an experimental drug called KLS-1, a form of zinc aspartate enriched with a specific zinc isotope, in adults with certain solid tumors (like melanoma, prostate, or pancreatic cancer) or chronic lymphocytic leukemia (CLL). The goal is to find the safest and most effective dose, understand how the drug behaves in the body, and see if it can shrink tumors or slow cancer growth. Participants receive KLS-1 through an IV every 21 days and are monitored for side effects and any signs of anti-tumor activity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
KLS-1, a solution of zinc aspartate enriched with the isotope zinc-64, given by intravenous infusion
What this could lead to
If KLS-1 proves safe and shows anti-tumor activity, it could become a new treatment option for certain advanced cancers and chronic lymphocytic leukemia.
What could go wrong
This is an early, small trial focused on safety and dosing, so it may not lead to an effective treatment. Potential side effects are not yet fully known.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Medical Centre of Arensia Exploratory Medicine LLC

    RECRUITING

    Kyiv, 01135, Ukraine

  • Medical and Diagnostic Center of Private Enterprise of Private Manufacturing Company "Acinus"

    RECRUITING

    Kropyvnytskyi, 25006, Ukraine

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