New imaging agent aims to light up hidden tumors

NCT ID NCT07664397

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study will test a new radioactive tracer called [89Zr]DFO-YS5 in 40 people with nerve sheath tumors, bladder cancer, or other advanced solid tumors. The tracer is designed to bind to cancer cells and show up on PET scans, potentially making tumors easier to see. The main goal is to measure how well the tracer highlights tumors compared to normal tissue, and to check for any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

[89Zr]DFO-YS5 (a radioactive tracer injected intravenously)

What this could lead to

If successful, this could improve how doctors see and locate certain cancers on PET scans, potentially aiding diagnosis.

What could go wrong

This is a very early (Phase 1) pilot study with only 40 people. It is designed to test imaging, not treatment, so it may not lead to any direct benefit for patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer carcinoma hypertrophic pyloric stenosis malignant peripheral nerve sheath tumor neoplasm nerve sheath neoplasm peripheral nervous system neoplasm urinary bladder carcinoma urinary bladder neoplasm Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact