Lab-Grown lymph node model reveals how CLL cells resist treatment

This study investigates how chronic lymphocytic leukemia (CLL) cells change their energy use when they are in the lymph node environment, which may help them resist standard treatments. Researchers are building a lab model using patient leukemia cells and normal lymph node cells to mimic this environment. They aim to understand why some CLL patients relapse and to test whether combining current drugs with metabolism-blocking therapies could be more effective.