New hope for Tough-to-Treat leukemia: phase 3 trial pits rocbrutinib against pirtobrutinib

NCT ID NCT07342478

First seen Jan 16, 2026 · Last updated May 09, 2026 · Updated 13 times

Summary

This study tests a new drug, rocbrutinib, against another drug, pirtobrutinib, in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has come back or not responded to prior treatments. About 306 adults will take one of the two pills daily to see which works better at controlling the cancer. The goal is to find a more effective option for patients who have already tried a BTK inhibitor.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • OSU Comprehensive Cancer Center

    NOT_YET_RECRUITING

    Columbus, Ohio, 43210, United States

  • Optum Medical Group (Rhodes) P.C.

    RECRUITING

    Las Vegas, Nevada, 89102, United States

  • UPMC Hillman Cancer Center

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

Conditions

Explore the condition pages connected to this study.