CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Clinical trials for CLL (CHRONIC LYMPHOCYTIC LEUKEMIA) explained in plain language.
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New combo aims to shorten CLL treatment
Disease control Recruiting nowThis phase 2 trial tests two oral drugs, zanubrutinib and sonrotoclax, in 24 people with untreated high-risk CLL/SLL. The goal is to see if a time-limited treatment guided by minimal residual disease (MRD) can achieve deep remission. Participants take the drugs for up to 27 cycle…
Matched conditions: CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Phase: PHASE2 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New drug rocbrutinib takes on pirtobrutinib in blood cancer showdown
Disease control Recruiting nowThis study tests a new drug, rocbrutinib, against another drug, pirtobrutinib, in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whose cancer has returned or stopped responding to treatment. All participants have already tried a type of BTK inh…
Matched conditions: CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Phase: PHASE3 • Sponsor: Newave Pharmaceutical Inc • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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4-Week vegan diet tested as CLL therapy
Disease control Recruiting nowThis study tests whether a 4-week whole-food plant-based diet can improve immune function and slow disease activity in people with early-stage chronic lymphocytic leukemia (CLL) who have not yet received treatment. Fifty participants will follow the diet and provide blood and sto…
Matched conditions: CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Phase: NA • Sponsor: Technical University of Munich • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New drug cocktails aim to tame transplant complications in blood cancer patients
Disease control Recruiting nowThis study tests whether new drug combinations can better prevent graft-versus-host disease (GVHD) in people with blood cancers who receive a stem cell transplant from a mismatched unrelated donor. About 358 participants will get either the standard GVHD prevention or one of two …
Matched conditions: CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Phase: PHASE2 • Sponsor: Center for International Blood and Marrow Transplant Research • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Could dead donors provide Life-Saving bone marrow?
Disease control Recruiting nowThis early study is testing whether bone marrow from deceased donors can be safely used for transplants in people with blood cancers like leukemia and lymphoma. Twelve patients will receive the transplant along with chemotherapy or radiation. The main goal is to see if the new ma…
Matched conditions: CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Phase: PHASE1, PHASE2 • Sponsor: Ossium Health, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New pill ZE50-0134 takes on Hard-to-Treat leukemia and lymphoma
Disease control Recruiting nowThis early-stage study is testing a new oral drug called ZE50-0134 in 66 adults with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or certain low-grade lymphomas that have come back or not responded to prior treatments. The main goal is to check the drug's…
Matched conditions: CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Phase: PHASE1 • Sponsor: Lomond Therapeutics Holdings, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Scientists watch and learn: no treatment, just tracking blood cancers over time
Knowledge-focused Recruiting nowThis study follows up to 1,000 adults with certain slow-growing blood cancers (CLL, SLL, LPL, WM) to track how the diseases change over time. Participants have regular check-ups and blood draws every 6 to 24 months, and may also have optional biopsies or scans for research. No tr…
Matched conditions: CLL (CHRONIC LYMPHOCYTIC LEUKEMIA)
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC