Centre Hospitalier Universitaire De Nice

This study aims to find out if getting a flu shot in the morning works better than in the evening for adults with chronic kidney failure. Researchers will compare the immune response and actual flu infections in about 735 patients who receive their vaccine at different times of d…

This study is testing if a drug called amiloride can help prevent the visual or sensory disturbances (aura) that some people experience before a migraine headache. It will involve 40 people in France who have frequent migraine with aura. Participants will try taking amiloride and…

This study is reviewing past medical records to understand how well the drug zilucoplan worked for 55 French patients with myasthenia gravis, a disease that causes severe muscle weakness. Researchers are looking at whether the treatment improved patients' daily function, muscle s…

This study is testing whether patients with uncomplicated appendicitis can safely go home the same day after surgery instead of staying in the hospital. It will compare the safety, recovery, and costs of outpatient care against the standard hospital stay. The goal is to free up h…

This study is testing whether a medication called bimekizumab, given as injections, can better control early plaque psoriasis and delay it from becoming a chronic, recurring condition compared to standard topical steroid creams. It will involve 40 adults aged 18-45 who have had m…

This study aims to improve treatment for membranous nephropathy, a serious autoimmune kidney disease. It will test if using a machine learning (AI) algorithm to predict which patients have too little medication in their system can help doctors give personalized, extra doses of ri…

This study observes 30 adults in France with a severe, life-threatening flare-up of myasthenia gravis (a rare muscle-weakening disease) who are already in the intensive care unit (ICU). Doctors want to see if giving a newer drug called ravulizumab early, after standard emergency …

This study is testing whether a newer drug called efgartigimod can help elderly patients with generalized myasthenia gravis reduce their steroid doses. Myasthenia gravis causes muscle weakness, and steroids are commonly used but cause serious side effects like diabetes and high b…

This study looks at whether adults with moderate-to-severe psoriasis who are responding well to guselkumab (Tremfya) injections can safely receive their treatments less frequently. Researchers are examining real-world data from 100 patients who have already extended their injecti…

This study is testing whether a computer can detect early signs of Alzheimer's disease by analyzing a person's speech patterns. Researchers will compare voice recordings from 100 adults (age 50+) with their existing medical test results. The goal is to create a simple voice test …

This study is testing whether women with pelvic organ prolapse (where pelvic organs drop from their normal position) can safely have a common mesh repair surgery and go home the same day, instead of staying in the hospital. Researchers will perform the surgery using either roboti…

This study is testing a new way to perform a minor tendon surgery to relieve pain that sometimes occurs after a total hip replacement. Doctors will use ultrasound imaging to guide the procedure instead of more complex surgical equipment, aiming for a simpler and faster operation.…

This study is testing whether a special stimulation device can help people recover balance and movement abilities after a recent stroke. Researchers will compare patients who receive active treatment with the device to those who use a non-active version. The goal is to see if thi…

This study tests two alternative pain management methods for shoulder dislocations in emergency rooms. Researchers are comparing a pain-relief inhaler (methoxyflurane) and a virtual reality headset against standard pain medications. The goal is to see if these methods can reduce …

This study is for adults with advanced blood cancers (MDS or AML) who are in palliative care and need regular blood transfusions. It compares two ways to decide when to give a transfusion: the usual method based on a blood count number, versus a new method based on changes in the…

This study is testing if a dietary supplement called L-tyrosine can help reduce anxiety and stress in adults having outpatient hernia surgery. Researchers want to see if taking L-tyrosine improves the body's ability to handle the stress of surgery without causing drowsiness or de…

This study is testing whether online health education workshops are a practical way to support French adolescents and young adults with cancer. Researchers will offer three digital workshops to 48 participants to help them manage the challenges of their diagnosis and treatment. T…

This study aims to understand the health needs of migrant and socially vulnerable people visiting a clinic in Nice, France. Researchers are interviewing participants to learn what barriers prevent them from joining group health activities and what might help them get involved. Th…

This study aims to understand why some melanoma skin cancers become resistant to immunotherapy treatments. Researchers will analyze tumor samples from 20 patients with advanced melanoma before and after they receive immunotherapy. By studying how cancer cells' energy systems chan…

This study aims to better understand serious Bacillus cereus infections in premature babies hospitalized in France. Researchers will analyze bacteria samples from 40 infected newborns to identify which strains are most dangerous and what factors lead to worse outcomes. The goal i…

This study aims to understand why some newborns experience rectal bleeding. Researchers will observe 40 babies in a French hospital to determine how many cases are caused by cow's milk allergy versus a temporary condition. The study only involves observation and data collection -…

This study aims to understand how cancer treatment affects sleep in young survivors aged 15-24. Researchers will survey 400 young people who finished cancer treatment at least 3 months ago to measure insomnia rates and identify sleep disorder risk factors. The study focuses on ga…

This study aims to understand how 'attentional tunneling'—a type of tunnel vision where a dentist focuses too narrowly on one problem—affects patient care and safety in France. Researchers will survey 160 French dental practitioners, including professors, surgeons, and interns, u…

This study looked at whether a school health education program might influence parents' decisions about the HPV vaccine for their children. Researchers compared vaccination consent and coverage data from one middle school that used the educational materials to general data from t…

This study aims to understand why some older adults benefit more from exercise than others. Researchers will test if personalized exercise plans, based on a person's physical and biological profile, lead to better muscle strength and health compared to standard exercise or no exe…

This study aims to understand if a liver transplant can stop or slow the hardening of arteries (calcification) in people with serious liver disease. Researchers will observe 95 patients who need a liver transplant, measuring artery health and a specific blood chemical before and …

This study aims to understand if different types of hormonal birth control affect the looseness (laxity) of knee ligaments in healthy women. Researchers will measure knee movement in 90 women aged 18-40, comparing those on different contraceptives and at different points in their…

This study aims to understand if people with lymphedema (chronic swelling) have higher levels of a specific blood marker called Lp(a), which is linked to heart disease. Researchers will test 100 adults with lymphedema to see how common this high marker is. The goal is to gather k…

This study aims to understand if digital tests and advanced brain scans can detect early signs of multiple sclerosis (MS) in people who show brain changes on MRI but have no symptoms. Researchers will compare 150 people with these early signs to people already diagnosed with MS w…