Could a pill and light combo beat vitiligo?

NCT ID NCT07152626

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking a daily pill (ritlecitinib) plus twice-weekly narrowband UVB light therapy works better than the pill alone for vitiligo. About 56 adults with non-segmental vitiligo covering 4-60% of their body will take part. The main goal is to see how much skin color returns on the face and body after 52 weeks of treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ritlecitinib (a JAK inhibitor pill) and narrowband UVB light therapy

What this could lead to

If this combination works better than the pill alone, it could offer a more effective treatment option for vitiligo, helping to restore skin color more quickly.

What could go wrong

This is a Phase 2 trial with only 56 participants, so results are still early. The added benefit of UVB may be small, and UVB requires frequent clinic visits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

vitiligo

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP

    RECRUITING

    Paris, Creteil, 94010, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU La Réunion

    RECRUITING

    La Réunion, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Bordeaux

    RECRUITING

    Bordeaux, 33000, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHu de Nice, Hôpital Archet

    RECRUITING

    Nice, Alpes-Maritime, 06200, France

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HCL

    RECRUITING

    Lyon, 69000, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••