Blood transfusions guided by how you feel, not just lab numbers

This study looks at whether using a simple quality-of-life questionnaire to decide when to give blood transfusions can reduce the number of transfusions needed for people with advanced myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) who are receiving palliative care. Currently, transfusions are given based on hemoglobin levels, but this may not always improve how patients feel. The trial will compare the standard approach with a new one that uses weekly patient-reported well-being scores. About 52 adults will take part, and researchers will track transfusion counts, quality of life, and survival over two months.